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Rat embryonic stem cells create new era in development of genetically manipulated rat models

Embryonic stem (ES) cells are isolated from the inner cell mass of a blastocyst, and are used for the generation of gene-modified animals. In mice, the transplantation of gene-modified ES cells into recipient blastocysts leads to the creation of gene-targeted mice such as knock-in and knock-out mice...

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Detalhes bibliográficos
Publicado no:World J Stem Cells
Main Authors: Kawaharada, Kazushi, Kawamata, Masaki, Ochiya, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550629/
https://ncbi.nlm.nih.gov/pubmed/26328021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4252/wjsc.v7.i7.1054
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