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Optimization of optical and mechanical properties of real architecture for 3-dimensional tissue equivalents: Towards treatment of limbal epithelial stem cell deficiency

Limbal epithelial stem cell (LESC) deficiency can cause blindness. Transplantation of cultured human limbal epithelial cells (hLE) on human amniotic membrane (HAM) can restore vision but clinical graft manufacture can be unreliable. We have developed a reliable and robust tissue equivalent (TE) alte...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Massie, Isobel, Kureshi, Alvena K., Schrader, Stefan, Shortt, Alex J., Daniels, Julie T.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550494/
https://ncbi.nlm.nih.gov/pubmed/26092352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2015.06.007
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