Metronidazole-triazole conjugates: Activity against Clostridium difficile and parasites

Metronidazole has been used clinically for over 50 years as an antiparasitic and broad-spectrum antibacterial agent effective against anaerobic bacteria. However resistance to metronidazole in parasites and bacteria has been reported, and improved second-generation metronidazole analogues are needed...

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Dettagli Bibliografici
Pubblicato in:Eur J Med Chem
Autori principali: Jarrad, Angie M., Karoli, Tomislav, Debnath, Anjan, Tay, Chin Yen, Huang, Johnny X., Kaeslin, Geraldine, Elliott, Alysha G., Miyamoto, Yukiko, Ramu, Soumya, Kavanagh, Angela M., Zuegg, Johannes, Eckmann, Lars, Blaskovich, Mark A.T., Cooper, Matthew A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Editions Scientifiques Elsevier 2015
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550478/
https://ncbi.nlm.nih.gov/pubmed/26117821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.06.019
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