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The c.503T>C Polymorphism in the Human KLRB1 Gene Alters Ligand Binding and Inhibitory Potential of CD161 Molecules

Studying genetic diversity of immunologically relevant molecules can improve our knowledge on their functional spectrum in normal immune responses and may also uncover a possible role of different variants in diseases. We characterized the c.503T>C polymorphism in the human KLRB1 gene (Killer cel...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rother, Sascha, Hundrieser, Joachim, Pokoyski, Claudia, Kollrich, Sonja, Borns, Katja, Blasczyk, Rainer, Poehnert, Daniel, Klempnauer, Jürgen, Schwinzer, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550425/
https://ncbi.nlm.nih.gov/pubmed/26309225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135682
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