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Angiopoietin-4 increases permeability of blood vessels and promotes lymphatic dilation

The angiopoietin (Ang) ligands are potential therapeutic targets for lymphatic related diseases, which include lymphedema and cancer. Ang-1 and Ang-2 functions are established, but those of Ang-4 are poorly understood. We used intravital fluorescence microscopy to characterize Ang-4 actions on T241...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Kesler, Cristina T., Pereira, Ethel R., Cui, Cheryl H., Nelson, Gregory M., Masuck, David J., Baish, James W., Padera, Timothy P.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550378/
https://ncbi.nlm.nih.gov/pubmed/25977256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-268920
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