FFCD-1004 Clinical Trial: Impact of Cytidine Deaminase Activity on Clinical Outcome in Gemcitabine-Monotherapy Treated Patients

PURPOSE: Because cytidine deaminase (CDA) is the key enzyme in gemcitabine metabolism, numerous studies have attempted to investigate impact of CDA status (i.e. genotype or phenotype) on clinical outcome. To date, data are still controversial because none of these studies has fully investigated geno...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Serdjebi, Cindy, Gagnière, Johan, Desramé, Jérôme, Fein, Francine, Guimbaud, Rosine, François, Eric, André, Thierry, Seitz, Jean-François, Montérymard, Carole, Arsene, Dominique, Volet, Julien, Abakar-Mahamat, Abakar, Lecomte, Thierry, Guerin-Meyer, Véronique, Legoux, Jean-Louis, Deplanque, Gaël, Guillet, Pierre, Ciccolini, Joseph, Lepage, Côme, Dahan, Laetitia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550302/
https://ncbi.nlm.nih.gov/pubmed/26308942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135907
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