FFCD-1004 Clinical Trial: Impact of Cytidine Deaminase Activity on Clinical Outcome in Gemcitabine-Monotherapy Treated Patients

PURPOSE: Because cytidine deaminase (CDA) is the key enzyme in gemcitabine metabolism, numerous studies have attempted to investigate impact of CDA status (i.e. genotype or phenotype) on clinical outcome. To date, data are still controversial because none of these studies has fully investigated geno...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Serdjebi, Cindy, Gagnière, Johan, Desramé, Jérôme, Fein, Francine, Guimbaud, Rosine, François, Eric, André, Thierry, Seitz, Jean-François, Montérymard, Carole, Arsene, Dominique, Volet, Julien, Abakar-Mahamat, Abakar, Lecomte, Thierry, Guerin-Meyer, Véronique, Legoux, Jean-Louis, Deplanque, Gaël, Guillet, Pierre, Ciccolini, Joseph, Lepage, Côme, Dahan, Laetitia
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4550302/
https://ncbi.nlm.nih.gov/pubmed/26308942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135907
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