Interleukin 12 induces the differentiation of major histocompatibility complex class I-primed cytotoxic T-lymphocyte precursors into allospecific cytotoxic effectors.

The production of interleukin 12 (IL-12) following allogeneic stimulation and its involvement in the differentiation of allospecific cytotoxic T lymphocytes (CTLs) have been investigated. Supernatants of mixed lymphocyte cultures had detectable levels of IL-12 p40 which were completely abrogated aft...

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Detalhes bibliográficos
Main Authors: Chouaib, S, Chehimi, J, Bani, L, Genetet, N, Tursz, T, Gay, F, Trinchieri, G, Mami-Chouaib, F
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC45498/
https://ncbi.nlm.nih.gov/pubmed/7809096
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