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Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design

Neuraminidase (NA) inhibitors are the dominant antiviral drugs for treating influenza in the clinic. Increasing prevalence of drug resistance makes the discovery of new NA inhibitors a high priority. Thirty-one triterpenoids from the medicinal mushroom Ganoderma lingzhi were analyzed in an in vitro...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Zhu, Qinchang, Bang, Tran Hai, Ohnuki, Koichiro, Sawai, Takashi, Sawai, Ken, Shimizu, Kuniyoshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549708/
https://ncbi.nlm.nih.gov/pubmed/26307417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13194
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