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Inhibition of neuraminidase by Ganoderma triterpenoids and implications for neuraminidase inhibitor design

Neuraminidase (NA) inhibitors are the dominant antiviral drugs for treating influenza in the clinic. Increasing prevalence of drug resistance makes the discovery of new NA inhibitors a high priority. Thirty-one triterpenoids from the medicinal mushroom Ganoderma lingzhi were analyzed in an in vitro...

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Publicat a:Sci Rep
Autors principals: Zhu, Qinchang, Bang, Tran Hai, Ohnuki, Koichiro, Sawai, Takashi, Sawai, Ken, Shimizu, Kuniyoshi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549708/
https://ncbi.nlm.nih.gov/pubmed/26307417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13194
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