Restoration of Physiologically Responsive Low-Density Lipoprotein Receptor-Mediated Endocytosis in Genetically Deficient Induced Pluripotent Stem Cells

Acquiring sufficient amounts of high-quality cells remains an impediment to cell-based therapies. Induced pluripotent stem cells (iPSC) may be an unparalleled source, but autologous iPSC likely retain deficiencies requiring correction. We present a strategy for restoring physiological function in ge...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Ramakrishnan, Venkat M., Yang, Jeong-Yeh, Tien, Kevin T., McKinley, Thomas R., Bocard, Braden R., Maijub, John G., Burchell, Patrick O., Williams, Stuart K., Morris, Marvin E., Hoying, James B., Wade-Martins, Richard, West, Franklin D., Boyd, Nolan L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549683/
https://ncbi.nlm.nih.gov/pubmed/26307169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep13231
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