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Proteins bound at adjacent DNA elements act synergistically to regulate human proenkephalin cAMP inducible transcription.

Synthesis of the endogenous opioid precursor, proenkephalin, is regulated by neurotransmitters and membrane depolarization. These events act through second messenger dependent signal transduction pathways via a short inducible DNA enhancer to regulate transcription of the proenkephalin gene. Two DNA...

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Bibliografiske detaljer
Main Authors: Comb, M, Mermod, N, Hyman, S E, Pearlberg, J, Ross, M E, Goodman, H M
Format: Artigo
Sprog:Inglês
Udgivet: 1988
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC454956/
https://ncbi.nlm.nih.gov/pubmed/2850173
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