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Effect of Chronic Blood Transfusion on Biomarkers of Coagulation Activation and Thrombin Generation in Sickle Cell Patients at Risk for Stroke

Hypercoagulability in sickle cell disease (SCD) is associated with multiple SCD phenotypes, association with stroke risk has not been well described. We hypothesized that serum levels of biomarkers of coagulation activation correlate with high transcranial Doppler ultrasound velocity and decreases w...

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Publicado en:PLoS One
Main Authors: Hyacinth, Hyacinth I., Adams, Robert J., Greenberg, Charles S., Voeks, Jenifer H., Hill, Allyson, Hibbert, Jacqueline M., Gee, Beatrice E.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549306/
https://ncbi.nlm.nih.gov/pubmed/26305570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0134193
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