Systems Genetics Reveals the Functional Context of PCOS Loci and Identifies Genetic and Molecular Mechanisms of Disease Heterogeneity

Genome wide association studies (GWAS) have revealed 11 independent risk loci for polycystic ovary syndrome (PCOS), a common disorder in young women characterized by androgen excess and oligomenorrhea. To put these risk loci and the single nucleotide polymorphisms (SNPs) therein into functional cont...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS Genet
मुख्य लेखकों: Jones, Michelle R., Brower, Meredith A., Xu, Ning, Cui, Jinrui, Mengesha, Emebet, Chen, Yii-Der I., Taylor, Kent D., Azziz, Ricardo, Goodarzi, Mark O.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2015
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549292/
https://ncbi.nlm.nih.gov/pubmed/26305227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005455
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