Systems Genetics Reveals the Functional Context of PCOS Loci and Identifies Genetic and Molecular Mechanisms of Disease Heterogeneity

Genome wide association studies (GWAS) have revealed 11 independent risk loci for polycystic ovary syndrome (PCOS), a common disorder in young women characterized by androgen excess and oligomenorrhea. To put these risk loci and the single nucleotide polymorphisms (SNPs) therein into functional cont...

Full description

Saved in:
Bibliographic Details
Published in:PLoS Genet
Main Authors: Jones, Michelle R., Brower, Meredith A., Xu, Ning, Cui, Jinrui, Mengesha, Emebet, Chen, Yii-Der I., Taylor, Kent D., Azziz, Ricardo, Goodarzi, Mark O.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549292/
https://ncbi.nlm.nih.gov/pubmed/26305227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005455
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items