Systems Genetics Reveals the Functional Context of PCOS Loci and Identifies Genetic and Molecular Mechanisms of Disease Heterogeneity

Genome wide association studies (GWAS) have revealed 11 independent risk loci for polycystic ovary syndrome (PCOS), a common disorder in young women characterized by androgen excess and oligomenorrhea. To put these risk loci and the single nucleotide polymorphisms (SNPs) therein into functional cont...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Genet
Prif Awduron: Jones, Michelle R., Brower, Meredith A., Xu, Ning, Cui, Jinrui, Mengesha, Emebet, Chen, Yii-Der I., Taylor, Kent D., Azziz, Ricardo, Goodarzi, Mark O.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549292/
https://ncbi.nlm.nih.gov/pubmed/26305227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005455
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