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Identification of Distinct Tumor Subpopulations in Lung Adenocarcinoma via Single-Cell RNA-seq

Single-cell sequencing, which is used to detect clinically important tumor subpopulations, is necessary for understanding tumor heterogeneity. Here, we analyzed transcriptomic data obtained from 34 single cells from human lung adenocarcinoma (LADC) patient-derived xenografts (PDXs). To focus on the...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Min, Jae-Woong, Kim, Woo Jin, Han, Jeong A., Jung, Yu-Jin, Kim, Kyu-Tae, Park, Woong-Yang, Lee, Hae-Ock, Choi, Sun Shim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549254/
https://ncbi.nlm.nih.gov/pubmed/26305796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135817
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