Binding of Vav to Grb2 through dimerization of Src homology 3 domains.
The protooncogenic protein Vav has the structure of an intracellular signal transducer. It is exclusively expressed in cells of hematopoietic lineage and plays a crucial role in hematopoietic cell differentiation. Here we report that both in cell extracts and within intact mammalian cells Vav binds...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45492/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7809090/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.26.12629 |
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