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Animal models for progressive multifocal leukoencephalopathy

Progressive multifocal leukoencephalopathy (PML) is a severe demyelinating disease of the CNS caused by the human polyomavirus JC (JCV). JCV replication occurs only in human cells and investigation of PML has been severely hampered by the lack of an animal model. The common feature of PML is impairm...

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Bibliographic Details
Published in:J Cell Physiol
Main Authors: White, Martyn K., Gordon, Jennifer, Berger, Joseph R., Khalili, Kamel
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549183/
https://ncbi.nlm.nih.gov/pubmed/26041694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25047
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