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Animal models for progressive multifocal leukoencephalopathy

Progressive multifocal leukoencephalopathy (PML) is a severe demyelinating disease of the CNS caused by the human polyomavirus JC (JCV). JCV replication occurs only in human cells and investigation of PML has been severely hampered by the lack of an animal model. The common feature of PML is impairm...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: White, Martyn K., Gordon, Jennifer, Berger, Joseph R., Khalili, Kamel
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549183/
https://ncbi.nlm.nih.gov/pubmed/26041694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25047
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