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The GIPC1-Akt1 pathway is required for the specification of the eye field in mouse embryonic stem cells

During early patterning of the neural plate, a single region of the embryonic forebrain, the eye field, becomes competent for eye development. The hallmark of eye field specification is the expression of the eye field transcription factors (EFTFs). Experiments in fish, amphibians, birds and mammals...

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Veröffentlicht in:Stem Cells
Hauptverfasser: La Torre, Anna, Hoshino, Akina, Cavanaugh, Christopher, Ware, Carol B., Reh, Thomas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549161/
https://ncbi.nlm.nih.gov/pubmed/26013465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2062
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