Age-Related Changes in Pre- and Postsynaptic Partners of the Cholinergic C-Boutons in Wild-Type and SOD1(G93A) Lumbar Motoneurons

Large cholinergic synaptic terminals known as C-boutons densely innervate the soma and proximal dendrites of motoneurons that are prone to neurodegeneration in amyotrophic lateral sclerosis (ALS). Studies using the Cu/Zn-superoxide dismutase (SOD1) mouse model of ALS have generated conflicting data...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Milan, Léa, Courtand, Gilles, Cardoit, Laura, Masmejean, Frédérique, Barrière, Grégory, Cazalets, Jean-René, Garret, Maurice, Bertrand, Sandrine S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549056/
https://ncbi.nlm.nih.gov/pubmed/26305672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135525
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