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Acacetin inhibits expression of matrix metalloproteinases via a MAPK-dependent mechanism in fibroblast-like synoviocytes

It is well known that rheumatoid arthritis (RA) is an autoimmune joint disease in which fibroblast-like synoviocytes (FLSs) play a pivotal role. In this study, we investigated the anti-arthritic properties of acacetin in FLSs. The expression of matrix metalloproteinase (MMP)-1, MMP-3 and MMP-13 were...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Chen, Wei-Ping, Yang, Zhi-Gao, Hu, Peng-Fei, Bao, Jia-Peng, Wu, Li-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4549041/
https://ncbi.nlm.nih.gov/pubmed/25856795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12564
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