CD40L expression permits CD8(+) T cells to execute immunologic helper functions

CD8(+) T cells play an essential role in immunity against intracellular pathogens, with cytotoxicity being considered their major effector mechanism. However, we here demonstrate that a major part of central and effector memory CD8(+) T cells expresses CD40L, one key molecule for CD4(+) T-cell–media...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Frentsch, Marco, Stark, Regina, Matzmohr, Nadine, Meier, Sarah, Durlanik, Sibel, Schulz, Axel R., Stervbo, Ulrik, Jürchott, Karsten, Gebhardt, Friedemann, Heine, Guido, Reuter, Morgan A., Betts, Michael R., Busch, Dirk, Thiel, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548794/
https://ncbi.nlm.nih.gov/pubmed/23719298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-02-483586
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