Diverse organization of immunoglobulin VH gene loci in a primitive vertebrate.

The immunoglobulin (Ig) heavy chain variable (VH) gene family of Heterodontus francisci (horned shark), a phylogenetically distant vertebrate, is unique in that VH, diversity (DH), joining (JH) and constant region (CH) gene segments are linked closely, in multiple individual clusters. The V regions...

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Bibliographic Details
Main Authors: Kokubu, F, Litman, R, Shamblott, M J, Hinds, K, Litman, G W
Format: Artigo
Language:Inglês
Published: 1988
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC454840/
https://ncbi.nlm.nih.gov/pubmed/3145194
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