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On the membrane translocation of diphtheria toxin: at low pH the toxin induces ion channels on cells.

Diphtheria toxin (DT) in acidic media forms ion-conducting channels across the plasma membrane and inhibits protein synthesis of both highly and poorly DT-sensitive cell lines. This results in loss of cell potassium and in entry of both sodium and protons with a concomitant rapid lowering of membran...

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Detalles Bibliográficos
Main Authors: Papini, E, Sandoná, D, Rappuoli, R, Montecucco, C
Formato: Artigo
Idioma:Inglês
Publicado: 1988
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC454832/
https://ncbi.nlm.nih.gov/pubmed/2463157
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