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Structure-based design of novel naproxen derivatives targeting monomeric nucleoprotein of Influenza A virus
The nucleoprotein (NP) binds the viral RNA genome as oligomers assembled with the polymerase in a ribonucleoprotein complex required for transcription and replication of influenza A virus. Novel antiviral candidates targeting the nucleoprotein either induced higher order oligomers or reduced NP olig...
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Publicado no: | J Biomol Struct Dyn |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Taylor & Francis
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4548311/ https://ncbi.nlm.nih.gov/pubmed/25333630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2014.979230 |
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