Impact of peroxisome proliferator-activated receptor γ on angiotensin II type 1 receptor-mediated insulin sensitivity, vascular inflammation and atherogenesis in hypercholesterolemic mice

INTRODUCTION: The angiotensin II type 1 receptor (AT1R) and the peroxisome proliferator-activated receptor γ (PPARγ) have been implicated in the pathogenesis of atherosclerosis. A number of studies have reported that AT1R inhibition or genetic AT1R disruption and PPARγ activation inhibit vascular in...

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Vydáno v:Arch Med Sci
Hlavní autoři: Tiyerili, Vedat, Becher, Ulrich M., Camara, Bakary, Yildirimtürk, Cihan, Aksoy, Adem, Kebschull, Moritz, Werner, Nikos, Nickenig, Georg, Müller, Cornelius
Médium: Artigo
Jazyk:Inglês
Vydáno: Termedia Publishing House 2015
Témata:
Experimental Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4548041/
https://ncbi.nlm.nih.gov/pubmed/26322101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2015.53309
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