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Data-driven modelling of a gene regulatory network for cell fate decisions in the growing limb bud

Parameter optimization coupled with model selection is a convenient approach to infer gene regulatory networks from experimental gene expression data, but so far it has been limited to single cells or static tissues where growth is not significant. Here, we present a computational study in which we...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Uzkudun, Manu, Marcon, Luciano, Sharpe, James
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547844/
https://ncbi.nlm.nih.gov/pubmed/26174932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20145882
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