The Presence of HLA-E-Restricted, CMV-Specific CD8(+) T Cells in the Blood of Lung Transplant Recipients Correlates with Chronic Allograft Rejection

The human cytomegalovirus (CMV) immune evasion protein, UL40, shares an identical peptide sequence with that found in the leader sequence of many human leukocyte antigen (HLA)-C alleles and when complexed with HLA-E, can modulate NK cell functions via interactions with the CD94-NKG2 receptors. Howev...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Sullivan, Lucy C., Westall, Glen P., Widjaja, Jacqueline M. L., Mifsud, Nicole A., Nguyen, Thi H. O., Meehan, Aislin C., Kotsimbos, Tom C., Brooks, Andrew G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547726/
https://ncbi.nlm.nih.gov/pubmed/26302084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135972
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