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RVD2: an ultra-sensitive variant detection model for low-depth heterogeneous next-generation sequencing data
Motivation: Next-generation sequencing technology is increasingly being used for clinical diagnostic tests. Clinical samples are often genomically heterogeneous due to low sample purity or the presence of genetic subpopulations. Therefore, a variant calling algorithm for calling low-frequency polymo...
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| Publicado no: | Bioinformatics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4547613/ https://ncbi.nlm.nih.gov/pubmed/25931517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv275 |
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