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Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities
Obesity and the metabolic syndrome have evolved to be major health issues throughout the world. Whether loss of genome integrity contributes to this epidemic is an open question. DNA polymerase η (pol η), encoded by the xeroderma pigmentosum (XP-V) gene, plays an essential role in preventing cutaneo...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4547227/ https://ncbi.nlm.nih.gov/pubmed/26240351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1506954112 |
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