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Physically-based in silico light sheet microscopy for visualizing fluorescent brain models

BACKGROUND: We present a physically-based computational model of the light sheet fluorescence microscope (LSFM). Based on Monte Carlo ray tracing and geometric optics, our method simulates the operational aspects and image formation process of the LSFM. This simulated, in silico LSFM creates synthet...

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Dettagli Bibliografici
Pubblicato in:BMC Bioinformatics
Autori principali: Abdellah, Marwan, Bilgili, Ahmet, Eilemann, Stefan, Markram, Henry, Schürmann, Felix
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547197/
https://ncbi.nlm.nih.gov/pubmed/26329404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S11-S8
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