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Rapid turnover of adenovirus E1A is determined through a co-translational mechanism that requires an aminoterminal domain.
The product of the adenovirus E1A 13S mRNA can both stimulate and repress the expression of certain viral and cellular genes. As with several other regulatory proteins, E1A has a short half-life, approximately 40 min. Although this short half-life is observed in cells expressing the E1A gene, it is...
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主要な著者: | , , |
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フォーマット: | Artigo |
言語: | Inglês |
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1988
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC454707/ https://ncbi.nlm.nih.gov/pubmed/2972538 |
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