Molecular docking based screening of novel designed chalcone series of compounds for their anti-cancer activity targeting EGFR kinase domain

Epidermal growth factor receptors (EGFR) are critical for the growth of many tumors and expressed at high levels in about one third of epithelial cancers. Hence, blockade of the binding sites for EGFR has been hypothesized as an effective anti-cancer therapy. Chalcone derivative compounds have been...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Bioinformation
Egile Nagusiak: Rao, Chennu Maruthi Malya Prasada, Yejella, Rajendra Prasad, Rehman, Rehman Shaik Abdul, Basha, Syed Hussain
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Biomedical Informatics 2015
Gaiak:
Hypothesis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546990/
https://ncbi.nlm.nih.gov/pubmed/26339147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.6026/97320630011322
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