Genetic and Diet-Induced Obesity Increased Intestinal Tumorigenesis in the Double Mutant Mouse Model Multiple Intestinal Neoplasia X Obese via Disturbed Glucose Regulation and Inflammation

We have studied how spontaneous or carcinogen-induced intestinal tumorigenesis was affected by genetic or diet-induced obesity in C57BL/6J-Apc (Min/+) X C57BL/6J-Lep (ob/+) mice. Obesity was induced by the obese (ob) mutation in the lep gene coding for the hormone leptin, or by a 45% fat diet. The e...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:J Obes
Auteurs principaux: Ngo, Ha Thi, Hetland, Ragna Bogen, Nygaard, Unni Cecilie, Steffensen, Inger-Lise
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546984/
https://ncbi.nlm.nih.gov/pubmed/26347815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/343479
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires