Influence of Olmesartan on Sirtuin 1 mRNA Expression in 5/6 Nephrectomized Spontaneously Hypertensive Rats

BACKGROUND: Recent studies revealed that sirtuin 1 (SIRT1) has a relation to the mechanism of transforming growth factor-beta (TGF-beta) mediated apoptosis in glomerular mesangial cells and plays an important role in blood pressure regulation. It has been suggested that SIRT1 contributes to the reno...

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Veröffentlicht in:Yonago Acta Med
Hauptverfasser: Takata, Tomoaki, Munemura, Chishio, Fukui, Takeaki, Fukuda, Satoko, Murawaki, Yoshikazu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Tottori University Faculty of Medicine 2015
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546957/
https://ncbi.nlm.nih.gov/pubmed/26306055
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