Molecular adjuvant IL-33 enhances the potency of a DNA vaccine in a lethal challenge model

Identifying new molecular adjuvants that elicit effective vaccine-induced CD8(+) T cell immunity may be critical for the elimination of many challenging diseases including Tuberculosis, HIV and cancer. Here, we report that co-administration of molecular adjuvant IL-33 during vaccination enhanced the...

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Veröffentlicht in:Vaccine
Hauptverfasser: Villarreal, Daniel O., Svoronos, Nikos, Wise, Megan C., Shedlock, Devon J., Morrow, Matthew P., Garcia, Jose-Conejo, Weiner, David B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546882/
https://ncbi.nlm.nih.gov/pubmed/25887087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.03.086
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