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Extent of systemic spread determines CD8(+) T cell immunodominance for laboratory strains, smallpox vaccines and zoonotic isolates of vaccinia virus()
CD8(+) T cells that recognize virus-derived peptides presented on MHC class I (pMHC) are vital anti-viral effectors. The pMHC presented by any given virus vary greatly in immunogenicity allowing them to be ranked in an immunodominance hierarchy. However, the full range of parameters that determine i...
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| Publicado en: | J Immunol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4546862/ https://ncbi.nlm.nih.gov/pubmed/26195812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402508 |
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