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Base Excision Repair in the Mitochondria
The 16.5 kb human mitochondrial genome encodes for 13 polypeptides, 22 tRNAs and 2 rRNAs involved in oxidative phosphorylation. Mitochondrial DNA (mtDNA), unlike its nuclear counterpart, is not packaged into nucleosomes and is more prone to the adverse effects of reactive oxygen species (ROS) genera...
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| Publicado no: | J Cell Biochem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4546830/ https://ncbi.nlm.nih.gov/pubmed/25754732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.25103 |
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