Invasion of ovarian cancer cells is induced byPITX2-mediated activation of TGF-β and Activin-A

BACKGROUND: Most ovarian cancers are highly invasive in nature and the high burden of metastatic disease make them a leading cause of mortality among all gynaecological malignancies. The homeodomain transcription factor, PITX2 is associated with cancer in different tissues. Our previous studies demo...

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Detalles Bibliográficos
Publicado en:Mol Cancer
Main Authors: Basu, Moitri, Bhattacharya, Rahul, Ray, Upasana, Mukhopadhyay, Satinath, Chatterjee, Uttara, Roy, Sib Sankar
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546816/
https://ncbi.nlm.nih.gov/pubmed/26298390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0433-y
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