Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection

Mucosa-associated invariant T (MAIT) cells represent a large innate-like evolutionarily conserved antimicrobial T-cell subset in humans. MAIT cells recognize microbial riboflavin metabolites from a range of microbes presented by MR1 molecules. MAIT cells are impaired in several chronic diseases incl...

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Publicado en:PLoS Pathog
Autores principales: Leeansyah, Edwin, Svärd, Jenny, Dias, Joana, Buggert, Marcus, Nyström, Jessica, Quigley, Máire F., Moll, Markus, Sönnerborg, Anders, Nowak, Piotr, Sandberg, Johan K.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546682/
https://ncbi.nlm.nih.gov/pubmed/26295709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005072
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