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Repression of the heat shock response is a programmed event at the onset of reproduction
The heat shock response (HSR) is essential for proteostasis and cellular health. In metazoans, aging is associated with a decline in quality control, thus increasing the risk for protein conformational disease. Here, we show that in C. elegans, the HSR declines precipitously over a four hour period...
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| Publicado no: | Mol Cell |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4546525/ https://ncbi.nlm.nih.gov/pubmed/26212459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.06.027 |
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