Llwytho...

Repression of the heat shock response is a programmed event at the onset of reproduction

The heat shock response (HSR) is essential for proteostasis and cellular health. In metazoans, aging is associated with a decline in quality control, thus increasing the risk for protein conformational disease. Here, we show that in C. elegans, the HSR declines precipitously over a four hour period...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell
Prif Awduron: Labbadia, Johnathan, Morimoto, Richard I
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546525/
https://ncbi.nlm.nih.gov/pubmed/26212459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.06.027
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