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Discovery, Annotation, and Functional Analysis of Long Noncoding RNAs Controlling Cell Cycle Gene Expression and Proliferation in Breast Cancer Cells

We describe a computational approach that integrates GRO-seq and RNA-seq data to annotate long noncoding RNAs (lncRNAs), with increased sensitivity for low abundance lncRNAs. We used this approach to characterize the lncRNA transcriptome in MCF-7 human breast cancer cells, including >700 previous...

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Bibliografski detalji
Izdano u:Mol Cell
Glavni autori: Sun, Miao, Gadad, Shrikanth S., Kim, Dae-Seok, Kraus, W. Lee
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546522/
https://ncbi.nlm.nih.gov/pubmed/26236012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.06.023
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