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Confusing Placebo Effect with Natural History in Epilepsy: A Big Data Approach

For unknown reasons, placebos reduce seizures in clinical trials in many patients. It is also unclear why some drugs showing statistical superiority to placebo in one trial may fail to do so in another. Using Seizuretracker.com, a patient-centered database of 684,825 seizures, we simulated “placebo”...

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Bibliografske podrobnosti
izdano v:Ann Neurol
Main Authors: Goldenholz, Daniel M., Moss, Robert, Scott, Jonathan, Auh, Sungyoung, Theodore, William H.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546516/
https://ncbi.nlm.nih.gov/pubmed/26150090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24470
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