Anticancer activity of halofuginone in a preclinical model of osteosarcoma: inhibition of tumor growth and lung metastases

Osteosarcoma is the main malignant primary bone tumor in children and adolescents for whom the prognosis remains poor, especially when metastases are present at diagnosis. Because we recently demonstrated that TGF-β/Smad cascade plays a crucial role in osteosarcoma metastatic progression, we investi...

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Udgivet i:Oncotarget
Main Authors: Lamora, Audrey, Mullard, Mathilde, Amiaud, Jérôme, Brion, Régis, Heymann, Dominique, Redini, Françoise, Verrecchia, Franck
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546476/
https://ncbi.nlm.nih.gov/pubmed/26015407
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