Ectopic expression of a novel CD22 splice-variant regulates survival and proliferation in malignant T cells from cutaneous T cell lymphoma (CTCL) patients

CD22 is a member of the Sialic acid-binding Ig-like lectin (Siglec) family of lectins described to be exclusively present in B lymphocytes and B cell-derived neoplasms. Here, we describe a novel splice form of CD22 (designated CD22ΔN), which lacks the N-terminal domain as demonstrated by exon-specif...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Bagdonaite, Ieva, Wandall, Hans H., Litvinov, Ivan V., Nastasi, Claudia, Becker, Jürgen C., Dabelsteen, Sally, Geisler, Carsten, Bonefeld, Charlotte M., Zhang, Qian, Wasik, Mariusz A., Zhou, Youwen, Sasseville, Denis, Ødum, Niels, Woetmann, Anders
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2015
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546473/
https://ncbi.nlm.nih.gov/pubmed/25957418
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