Ectopic expression of a novel CD22 splice-variant regulates survival and proliferation in malignant T cells from cutaneous T cell lymphoma (CTCL) patients

CD22 is a member of the Sialic acid-binding Ig-like lectin (Siglec) family of lectins described to be exclusively present in B lymphocytes and B cell-derived neoplasms. Here, we describe a novel splice form of CD22 (designated CD22ΔN), which lacks the N-terminal domain as demonstrated by exon-specif...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bagdonaite, Ieva, Wandall, Hans H., Litvinov, Ivan V., Nastasi, Claudia, Becker, Jürgen C., Dabelsteen, Sally, Geisler, Carsten, Bonefeld, Charlotte M., Zhang, Qian, Wasik, Mariusz A., Zhou, Youwen, Sasseville, Denis, Ødum, Niels, Woetmann, Anders
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546473/
https://ncbi.nlm.nih.gov/pubmed/25957418
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados