Ectopic expression of a novel CD22 splice-variant regulates survival and proliferation in malignant T cells from cutaneous T cell lymphoma (CTCL) patients

CD22 is a member of the Sialic acid-binding Ig-like lectin (Siglec) family of lectins described to be exclusively present in B lymphocytes and B cell-derived neoplasms. Here, we describe a novel splice form of CD22 (designated CD22ΔN), which lacks the N-terminal domain as demonstrated by exon-specif...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Bagdonaite, Ieva, Wandall, Hans H., Litvinov, Ivan V., Nastasi, Claudia, Becker, Jürgen C., Dabelsteen, Sally, Geisler, Carsten, Bonefeld, Charlotte M., Zhang, Qian, Wasik, Mariusz A., Zhou, Youwen, Sasseville, Denis, Ødum, Niels, Woetmann, Anders
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546473/
https://ncbi.nlm.nih.gov/pubmed/25957418
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