Necrosis targeted radiotherapy with iodine-131-labeled hypericin to improve anticancer efficacy of vascular disrupting treatment in rabbit VX2 tumor models

A viable rim of tumor cells surrounding central necrosis always exists and leads to tumor recurrence after vascular disrupting treatment (VDT). A novel necrosis targeted radiotherapy (NTRT) using iodine-131-labeled hypericin ((131)I-Hyp) was specifically designed to treat viable tumor rim and improv...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shao, Haibo, Zhang, Jian, Sun, Ziping, Chen, Feng, Dai, Xu, Li, Yaming, Ni, Yicheng, Xu, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546464/
https://ncbi.nlm.nih.gov/pubmed/26036625
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