The Absence of CYP3A5*3 Is a Protective Factor to Anticonvulsants Hypersensitivity Reactions: A Case-Control Study in Brazilian Subjects

Although aromatic anticonvulsants are usually well tolerated, they can cause cutaneous adverse drug reactions in up to 10% of patients. The clinical manifestations of the antiepileptics-induced hypersensitivity reactions (AHR) vary from mild skin rashes to severe cutaneous drug adverse reactions whi...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tanno, Luciana Kase, Kerr, Daniel Shikanai, dos Santos, Bernardo, Talib, Leda Leme, Yamaguti, Célia, Rodrigues, Helcio, Gattaz, Wagner Farid, Kalil, Jorge
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546353/
https://ncbi.nlm.nih.gov/pubmed/26291084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136141
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