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High-throughput methods for identification of protein-protein interactions involving short linear motifs

Interactions between modular domains and short linear motifs (3–10 amino acids peptide stretches) are crucial for cell signaling. The motifs typically reside in the disordered regions of the proteome and the interactions are often transient, allowing for rapid changes in response to changing stimuli...

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Pubblicato in:Cell Commun Signal
Autori principali: Blikstad, Cecilia, Ivarsson, Ylva
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546347/
https://ncbi.nlm.nih.gov/pubmed/26297553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-015-0116-8
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