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HIV-1 protease cleaves the serine-threonine kinases RIPK1 and RIPK2

BACKGROUND: HIV-1 protease (PR) is essential for viral infectivity as it cleaves Gag and Gag-Pol polyprotein precursors during viral maturation. Recent evidence suggests that cellular proteins can also be cleaved by PR, perhaps representing an important viral strategy to counter host defense mechani...

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Publicat a:Retrovirology
Autors principals: Wagner, Roland N., Reed, John C., Chanda, Sumit K.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546280/
https://ncbi.nlm.nih.gov/pubmed/26297639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0200-6
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