Polymorphic variation of hypoxia inducible factor-1 A (HIF1A) gene might contribute to the development of knee osteoarthritis: a pilot study

BACKGROUND: Osteoarthritis (OA) is a multifactorial degenerative condition of the whole joint with a complex pathogenesis whose development and progression is significantly mediated by interactions between the joint cartilage and articular tissues, particularly, proinflammatory mediators and oxidati...

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Pubblicato in:BMC Musculoskelet Disord
Autori principali: Fernández-Torres, Javier, Hernández-Díaz, Cristina, Espinosa-Morales, Rolando, Camacho-Galindo, Javier, Galindo-Sevilla, Norma del Carmen, López-Macay, Ámbar, Zamudio-Cuevas, Yessica, Martínez-Flores, Karina, Santamaría-Olmedo, Mónica Guadalupe, Pineda, Carlos, Granados, Julio, Martínez-Nava, Gabriela Angélica, Gutiérrez, Marwin, López-Reyes, Alberto G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546180/
https://ncbi.nlm.nih.gov/pubmed/26293784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-015-0678-z
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